A Phase 3, Double-Blind Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Status: Recruiting
Location: See all (169) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent Phase 3 studies (INCB 54707-301 \[NCT05620823\] or INCB 54707-302 \[NCT05620836\]).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Completion of the study treatment period of the originating parent study (INCB 54707-301 or INCB 54707-302).
• Agreement to use contraception.
• Willing and able to comply with the study protocol and procedures.
• Further inclusion criteria apply.
Locations
United States
Arkansas
Investigative Site US307
RECRUITING
Fort Smith
Investigative Site US214
RECRUITING
Rogers
Arizona
Investigative Site US303
RECRUITING
Phoenix
Investigative Site US240
RECRUITING
Scottsdale
California
Investigative Site US315
RECRUITING
Laguna Niguel
Investigative Site US223
RECRUITING
Los Angeles
Investigative Site US222
RECRUITING
Oakland
Investigative Site US226
RECRUITING
San Diego
Washington, D.c.
Investigative Site US233
WITHDRAWN
Washington D.c.
Florida
Investigative Site US309
RECRUITING
Clearwater
Investigative Site US317
RECRUITING
Hialeah
Investigative Site US306
RECRUITING
Hollywood
Investigative Site US320
RECRUITING
Hollywood
Investigative Site US316
RECRUITING
Maitland
Investigative Site US227
COMPLETED
Margate
Investigative Site US204
RECRUITING
Miami
Investigative Site US236
RECRUITING
Miami
Investigative Site US321
RECRUITING
North Miami Beach
Investigative Site US200
RECRUITING
Ocala
Investigative Site US201
RECRUITING
Tampa
Investigative Site US228
RECRUITING
Tampa
Georgia
Investigative Site US311
RECRUITING
Marietta
Illinois
Investigative Site US220
RECRUITING
West Dundee
Indiana
Investigative Site US206
RECRUITING
Indianapolis
Investigative Site US337
RECRUITING
Indianapolis
Kentucky
Investigative Site US341
NOT_YET_RECRUITING
Bowling Green
Investigative Site US209
RECRUITING
Louisville
Louisiana
Investigative Site US305
RECRUITING
Baton Rouge
Investigative Site US207
RECRUITING
Metairie
Investigative Site US229
RECRUITING
New Orleans
Massachusetts
Investigative Site US225
RECRUITING
Boston
Investigative Site US304
RECRUITING
Boston
Investigative Site US310
RECRUITING
Brighton
Investigative Site US221
RECRUITING
Quincy
Maryland
Investigative Site US224
RECRUITING
Baltimore
Investigative Site US325
RECRUITING
Marriottsville
Michigan
Investigative Site US213
RECRUITING
Fort Gratiot
Investigative Site US217
RECRUITING
Waterford
Minnesota
Investigative Site US212
RECRUITING
Minneapolis
Missouri
Investigative Site US302
RECRUITING
St Louis
North Carolina
Investigative Site US205
RECRUITING
Chapel Hill
Nebraska
Investigative Site US239
WITHDRAWN
Omaha
New Hampshire
Investigative Site US318
RECRUITING
Portsmouth
New Jersey
Investigative Site US230
RECRUITING
East Windsor
New York
Investigative Site US324
RECRUITING
Kew Gardens
Investigative Site US202
RECRUITING
New York
Investigative Site US210
RECRUITING
Rochester
Ohio
Investigative Site US215
RECRUITING
Bexley
Investigative Site US339
RECRUITING
Bexley
Investigative Site US330
RECRUITING
Boardman
Investigative Site US314
RECRUITING
Cincinnati
Investigative Site US312
RECRUITING
Cleveland
Investigative Site US203
RECRUITING
Gahanna
Oregon
Investigative Site US301
RECRUITING
Portland
Tennessee
Investigative Site US232
COMPLETED
Murfreesboro
Texas
Investigative Site US235
RECRUITING
Arlington
Investigative Site US218
RECRUITING
Bellaire
Investigative Site US340
RECRUITING
Bellaire
Investigative Site US238
RECRUITING
Pflugerville
Investigative Site US300
RECRUITING
Plano
Investigative Site US234
RECRUITING
San Antonio
Virginia
Investigative Site US313
RECRUITING
Norfolk
Washington
Investigative Site US308
RECRUITING
Spokane
Other Locations
Australia
Investigative Site AU201
RECRUITING
Carlton
Investigative Site AU203
RECRUITING
Charlestown
Investigative Site AU205
RECRUITING
Kogarah
Investigative Site AU200
RECRUITING
Liverpool
Investigative Site AU204
RECRUITING
Melbourne
Investigative Site AU206
COMPLETED
Woolloongabba
Investigative Site AU207
RECRUITING
Woolloongabba
Austria
Investigative Site AT306
RECRUITING
Inssbruck
Investigative Site AT303
WITHDRAWN
Vienna
Investigative Site AT305
RECRUITING
Vienna
Belgium
Investigative Site BE300
RECRUITING
Brussels
Investigative Site BE301
RECRUITING
Ghent
Investigative Site BE302
RECRUITING
Liège
Bulgaria
Investigative Site BG200
RECRUITING
Sofia
Investigative Site BG202
RECRUITING
Sofia
Investigative Site BG203
RECRUITING
Sofia
Investigative Site BG204
RECRUITING
Sofia
Investigative Site BG201
RECRUITING
Stara Zagora
Canada
Investigative Site CA304
RECRUITING
Barrie
Investigative Site CA202
RECRUITING
Calgary
Investigative Site CA204
RECRUITING
Edmonton
Investigative Site CA205
RECRUITING
Fredericton
Investigative Site CA308
RECRUITING
Hamilton
Investigative Site CA303
RECRUITING
London
Investigative Site CA207
RECRUITING
Mississauga
Investigative Site CA307
RECRUITING
Montreal
Investigative Site CA302
RECRUITING
Peterborough
Investigative Site CA208
RECRUITING
Richmond Hill
Investigative Site CA206
RECRUITING
Saint-jérôme
Investigative Site CA203
RECRUITING
St. John's
Investigative Site CA200
COMPLETED
Surrey
Investigative Site CA301
RECRUITING
Winnipeg
Denmark
Investigative Site DK200
RECRUITING
Århus N
Investigative Site DK201
RECRUITING
Roskilde
France
Investigative Site FR305
RECRUITING
Bordeaux
Investigative Site FR303
RECRUITING
Brest
Investigative Site FR205
RECRUITING
Dijon
Investigative Site FR307
RECRUITING
Le Mans
Investigative Site FR204
RECRUITING
Lyon
Investigative Site FR304
RECRUITING
Marseille
Investigative Site FR302
RECRUITING
Nantes
Investigative Site FR203
RECRUITING
Nice
Investigative Site FR300
RECRUITING
Paris
Investigative Site FR206
RECRUITING
Reims
Investigative Site FR202
RECRUITING
Rouen
Investigative Site FR301
RECRUITING
Saint-priest-en-jarez
Investigative Site FR306
RECRUITING
Toulouse
Germany
Investigative Site DE202
RECRUITING
Berlin
Investigative Site DE203
RECRUITING
Bochum
Investigative Site DE305
RECRUITING
Darmstadt
Investigative Site DE201
RECRUITING
Dessau
Investigative Site DE302
RECRUITING
Dresden
Investigative Site DE306
RECRUITING
Düsseldorf
Investigative Site DE207
RECRUITING
Erlangen
Investigative Site DE301
RECRUITING
Frankfurt
Investigative Site DE208
RECRUITING
Göttingen
Investigative Site DE303
RECRUITING
Hamburg
Investigative Site DE300
RECRUITING
Hanover
Investigative Site DE205
RECRUITING
Heidelberg
Investigative Site DE200
RECRUITING
Kiel
Investigative Site DE307
COMPLETED
Memmingen
Investigative Site DE206
RECRUITING
Merzig
Greece
Investigative Site GR300
RECRUITING
Athens
Investigative Site GR303
RECRUITING
Athens
Investigative Site GR302
RECRUITING
Thessaloniki
Italy
Investigative Site IT200
RECRUITING
Ancona
Investigative Site IT207
RECRUITING
Catania
Investigative Site IT202
RECRUITING
Milan
Investigative Site IT203
WITHDRAWN
Naples
Investigative Site IT206
RECRUITING
Pisa
Investigative Site IT205
RECRUITING
Roma
Investigative Site IT201
RECRUITING
Rozzano
Japan
Investigative Site JP301
RECRUITING
Ginowan-shi
Investigative Site JP304
RECRUITING
Itabashi-ku
Investigative Site JP305
RECRUITING
Kurume-shi
Investigative Site JP300
RECRUITING
Kyoto
Investigative Site JP303
RECRUITING
Niigata
Investigative Site JP308
RECRUITING
Sapporo
Investigative Site JP302
RECRUITING
Sendai
Investigative Site JP309
RECRUITING
Shinjuku-ku
Netherlands
Investigative Site NL302
RECRUITING
Breda
Investigative Site NL303
RECRUITING
Groningen
Investigative Site NL301
RECRUITING
Rotterdam
Poland
Investigative Site PL203
RECRUITING
Lublin
Investigative Site PL304
RECRUITING
Ostrowiec Świętokrzyski
Investigative Site PL200
RECRUITING
Rzeszów
Investigative Site PL201
RECRUITING
Warsaw
Investigative Site PL202
RECRUITING
Warsaw
Investigative Site PL301
RECRUITING
Wroclaw
Investigative Site PL302
RECRUITING
Wroclaw
Spain
Investigative Site ES203
COMPLETED
Alicante
Investigative Site ES302
RECRUITING
Badalona
Investigative Site ES303
RECRUITING
Barcelona
Investigative Site ES301
RECRUITING
Granada
Investigative Site ES202
RECRUITING
Las Palmas De Gran Canaria
Investigative Site ES201
RECRUITING
Madrid
Investigative Site ES204
WITHDRAWN
Madrid
Investigative Site ES205
RECRUITING
Madrid
Investigative Site ES305
RECRUITING
Madrid
Investigative Site ES200
RECRUITING
Manises
Investigative Site ES300
RECRUITING
Pontevedra
Investigative Site ES304
RECRUITING
Santiago De Compostela
United Kingdom
Investigative Site GB202
RECRUITING
Birmingham
Investigative Site GB200
RECRUITING
Dudley
Investigative Site GB201
WITHDRAWN
Leeds
Investigative Site GB203
RECRUITING
Salford
Contact Information
Primary
Incyte Corporation Call Center (US)
medinfo@incyte.com
1.855.463.3463
Backup
Incyte Corporation Call Center (ex-US)
eumedinfo@incyte.com
+800 00027423
Time Frame
Start Date: 2024-01-30
Estimated Completion Date: 2026-12-26
Participants
Target number of participants: 960
Treatments
Experimental: Cohort A
Povorcitinib at the protocol-defined dose strength based on cohort assignment.
Experimental: Cohort B
Povorcitinib at the protocol-defined dose strength based on cohort assignment.
Experimental: Cohort C
Povorcitinib at the protocol-defined dose strength based on cohort assignment.
Related Therapeutic Areas
Sponsors
Leads: Incyte Corporation